Small Bowel Endoscopic, Dallas Procedures


The proximal small bowel plays an important role in glucose homeostasis. Therefore, small bowel EBMTs may contribute to weight loss as well as diabetes improvement.

Analogues of Roux-en-Y Gastric Bypass (RYGB)

RYGB was developed by Mason and Ito in 1967. Since then, the procedure has undergone several technical modifications and has been a preferred bariatric procedure for the past several decades. During RYGB, the stomach is divided into a 20–30 mL pouch and a larger remnant stomach.
There have been three Endoscopic, Dallas devices that attempt to mimic elements of RYGB. These are Endoluminal Bypass, EndoBarrier and Duodenal Mucosal Resurfacing.

Endoluminal Bypass

The Endoluminal Bypass is a 120 cm sleeve secured at the gastroesophageal (GE) junction to create an endoluminal gastro-duodeno-jejunal bypass that mimics the permanent anatomical changes of RYGB. The company is currently planning a U.S. trial.

EndoBarrier

The EndoBarrier (GI Dynamics Inc., Lexington, MA), also known as duodenal-jejunal bypass sleeve (DJBS), is a 60 cm fluoropolymer sleeve that is anchored at the duodenal bulb and terminates at the proximal jejunum.

Duodenal Mucosal Resurfacing

Duodenal Mucosal Resurfacing (DMR) (Fractyl Laboratories, Cambridge, MA), or the Revita procedure, is an Endoscopic, Dallas procedure that applies radiofrequency to thermally ablate the superficial duodenal mucosa .
 Currently, a multi-center study is being conducted in Europe and a U.S. pivotal trial is planned.

Analogue of Variant Biliopancreatic Diversion-Duodenal Switch (BPD-DS)

Biliopancreatic diversion (BPD) was first described by Scopinaro in 1979. It consists of a horizontal gastrectomy, which leaves an upper stomach that is connected to the distal 250 cm small intestine.
The Incisionless Anastomotic System (IAS) is used to create an enteral diversion that is functionally similar to the variant DS procedure and mechanistically similar to ileal transposition.

Incisionless Anastomotic System (IAS)

IAS (GI Windows, Boston, MA) creates an anastomosis via incisionless magnetic compression. This technology has many applications including a bariatric dual-path enteral diversion procedure.

Other Small Bowel Procedures

SatiSphere

SatiSphere (Endosphere, Columbus, OH) consists of a nitinol memory wire with two pigtals at each end, and several polyethylenterephtalat spheres along the wire.

Conclusion

EBMTs have the potential to transform the treatment of obesity, which remains a growing pandemicFurthermore, as obesity is a chronic disease, these less invasive and reversible options may allow sequential therapy to more optimally manage this condition in the long-term.



Comments

Post a Comment

Popular posts from this blog

Best Clinic to get Coronary Artery Disease Treatment in Waco, TX

Image
What is coronary artery disease? Coronary artery disease (CAD) is a condition in which plaque builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque can harden or rupture, leading to a heart attack or stroke. CAD is a common type of heart disease. It is the leading cause of death in the United States for both men and women. CAD can cause angina (chest pain) or a heart attack. A heart attack happens when plaque ruptures and a blood clot forms in the artery, blocking blood flow to the heart muscle. What are the symptoms of coronary artery disease? Coronary artery disease (CAD) is a condition in which the arteries that supply blood to the heart become narrowed and hardened. This can lead to chest pain (angina), shortness of breath, heart attacks, and even death. CAD is a major cause of death in both men and women in the United
Read more

Top Reasons to Use an HTML Gmail Signature Generator for Your Business

Image
Email communication has become an essential part of daily business operations. As such, it's critical to make a good impression with every email you send. One way to achieve this is through a professional email signature. However, creating a polished and professional-looking signature can be time-consuming and frustrating. That's where an HTML GmailSignature Generator comes in. In this article, we'll discuss the benefits of using an HTML Gmail Signature Generator, including how it can save you time and effort, ensure consistent branding, and provide a mobile-friendly, professional look. We'll also introduce Hupport, which we believe is the best HTML Gmail Signature Generator available. Saves Time and Effort Creating an email signature from scratch can be time-consuming and frustrating, especially if you're not familiar with HTML or graphic design. With an HTML Gmail Signature Generator, you can save time and effort by automating the process. All you need to
Read more

Step-by-Step Guide to Creating a Professional Email Signature with a Generator

Image
An email signature is a crucial part of any email you send. It's an opportunity to showcase your professionalism and provide relevant information to the recipient. However, creating a professional email signature can be challenging, especially if you don't have any design skills. Fortunately, with the help of an email signature generator , you can create a professional-looking email signature in no time. In this article, we'll guide you through the steps of creating a professional email signature with a generator. Step 1: Choose an email signature generator There are many email signature generators available in the market, but not all of them are equal. You want to choose an email signature generator that is easy to use, provides customizable templates, and offers professional designs. Hupport is one such email signature generator that ticks all the boxes. Step 2: Enter your information Once you've chosen an email signature generator, the next step is to enter your inf
Read more